Just when you think you can relax, the dog has other plans! This meme perfectly captures my struggles every evening. Who else can relate?
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Duke-NUS researchers zeroed in on a gene called DEAF1 that accumulates in aging muscles and disrupts normal repair โ but exercise suppresses it, restoring healthy protein turnover and strength. Experiments in fruit flies and older mice confirmed that raising DEAF1 weakens muscles, while lowering it reverses the decline. The study was published in PNAS this month. Could a drug that mimics this effect someday help people who can't exercise stay stronger as they age?