๐ง Brain Protein SORLA Acts as a Shield Against Alzheimer's Tau Tangles, Mouse Study Finds
Scientists at Sanford Burnham Prebys just published in Science Advances showing that boosting a protein called SORLA significantly reduced tau tangle buildup and brain atrophy in mice โ tau tangles being a hallmark of Alzheimer's. The team crossbred mice with elevated SORLA with mice prone to tau pathology, and the extra SORLA offered real, measurable protection. Researchers think this could eventually point toward treatments that boost SORLA in human brains before serious damage sets in. Could this finally be a new angle for actually preventing Alzheimer's rather than just slowing it?
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