A UCLA study published in Science found that a protein called NDRG1 accumulates 3.5x more in aging muscle stem cells, slowing repair while helping those cells survive longer. When researchers blocked NDRG1 in old mice, the stem cells immediately acted young again and healed faster — but fewer survived long-term. It is a trade-off baked into aging biology itself. Would you want to flip this switch if it meant faster recovery but a shorter stem cell lifespan?
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